Dr. Gábor Vlád

Availability

Address: Sanofi-Aventis Hungary, Chinoin Inc.

Research&Development

Tó utca 1-5, Budapest, Hungary, H-1045.

Phone: laboratory: 00-36-1-505-1489, mobile: 00-36-70-381-0218.

Fax: 00-36-1-505-2632

E-mail: gabor.vlad@sanofi-aventis.com

Web: http://vg.web.elte.hu

Personal Data

• Place and Date of Birth: Budapest, Hungary, April 29, 1979.
• Marital Status: Married to Beatrix Bostai

Education

• 1993-1997: Eötvös József Secondary School, Budapest, Hungary
• 1997: Certificate of Secondary Education in Chemistry&Biology Section, Eötvös József Secondary School
• 1997-2002: Chemist Student, Eötvös Loránd University of Sciences, Budapest, Hungary
• 2002: M.Sc. in Chemistry, Eötvös Loránd University of Sciences

Title: The Efficient Synthesis of 2,2’-Bipyrimidine and Its Derivatives

Thesis Supervisor: Prof. István T. Horváth

• 2002-2005 : PhD Student (Government Grant), Eötvös Loránd University of Sciences, Budapest, Hungary

Thesis Supervisor: Prof. István T. Horváth

• 2006: PhD in Chemistry (summa cum laude), Eötvös Loránd University of Sciences

Title: Investigation of the Cyclo-Oligomerization of Alkyl Isocyanates and Synthesis of Fluorous Trialkylphosphines PDF

Thesis Supervisor: Prof. István T. Horváth

Current Research Interest

• Scalable Total Synthesis of Drug Molecules
• Preparation of Partially and Completely Perfuoroalkylated Aliphatic Phosphines and Phosphonium Salts
• Preparation of Chiral Fluorous Aliphatic Phosphines
• Preparation and Application of Chiral Fluorous Binaphtyl-based Phosphines in Biphasical Homogeneous Catalytic Systems
• Investigation of the Olygomerization of Hexylisocyanate by in situ IR- and NMR-Spectroscopy
• Catalyst Development for the Alternating Copolymerizaton of Carbondioxide and Epoxides
• Synthesis of Cubane-substituted Phosphines

Internships

• 2003, July-August: Bayer AG, BPO-IIS-INN-PUR-ALC, Leverkusen, Germany; Thesis Advisor: Dr. Frank U. Richter
• 2005, August: Bayer AG, BMS-INN-ALC, Leverkusen, Germany; Thesis Advisor: Dr. Frank U. Richter

Oral Presentations

• The Efficient Synthesis of 2,2’-Bipyrimidine (Gábor Vlád), Scientific Student Conference, ELTE, Budapest, Hungary, 2000.
• The Efficient Synthesis of 2,2’-Bipyrimidine (Gábor Vlád), Hungarian Scientific Student Conference, SZIE, Gödöllő, Hungary, 2001.
• Green Catalytic Synthesis of Dimethyl Carbonate (Szilárd Csihony, László T. Mika, Gábor Vlád, Katalin Barta, Christian T. Mehnert, István T. Horváth), 227th ACS National Meeting, Abstracts of Papers, INOR-1015, Anaheim, CA, United States, 2004.
• Country Report of Hungary (Bostai Beatrix, Polgár Tímea, Gábor Vlád), Molecular Modeling and Computer Assisted Combinatorial Chemistry Training Course, Trieste, Italy, 2004.
• Synthesis of Fluorous Phosphines (Gábor Vlád, Joan Fraga-Dubreuil, Norbert Farkas, Frank U. Richter, István T. Horváth), 1st International Symposium on Fluorous Technologies, Bordeaux, France, 2005.
• Novel HDI-Uretdiones - Reactive Diluents and Building Blocks (Frank U. Richter, Reinhard Halpaap, Andreas Hecking, Bernd Sojka, Josef Sanders, Thomas Stingl, Martin Melchiors, Nicolas Stoeckel, Jan Weikard and Andrea Bodor, Gábor Vlád, István T. Horváth), International Waterborne, High-Solids, and Powder Coatings Symposium, New Orleans, LA, United States, 2006.

Posters

• Improved Synthesis of 2,2’-Bipyrimidine, Gábor Vlád and István T. Horváth, 5th Summer School on Green Chemistry, Venice, Italy, 2002.
• Modular Synthesis of Fluorous Trialkylphosphines, Gábor Vlád, Frank Richter, István T. Horváth, 15th Summer School on Coordinational Chemistry, Szklarska Poręba, Poland, 2004.
• Synthesis of Fluorous Trialkylphosphines (Gábor Vlád, Joan Fraga-Dubreuil, Norbert Farkas, Frank U. Richter, István T. Horváth), 1st International Symposium on Fluorous Technologies, Bordeaux, France, 2005.

Publications

• The 12 Principles of Green Chemistry

Katalin Barta, Márton Csékei, Szilárd Csihony, Hasan Mehdi, István T. Horváth, Zoltán Pusztai, Gábor Vlád, Hun. Chem. J., 2000, 55, 173-181.

• Improved Synthesis of 2,2’-Bipyrimidine

Gábor Vlád and István T. Horváth, J. Org. Chem., 2002, 67(18), 6550-6552. PDF

• Modular Synthesis of Fluorous Trialkylphosphines

Gábor Vlád, Frank Richter, and István T. Horváth, Org. Lett., 2004, 6(24), 4559-4561. PDF +Supporting Information

• Synthesis of Fluorous Trialkyl Phosphines with the Complete Exclusion of PH₃

Gábor Vlád, Frank Richter, and István T. Horváth, Tetrahedron Lett., 2005, 46, 8605-8608. PDF +Supplementary Data

• In situ NMR Spectroscopic Observation of a Catalytic Intermediate in Phosphine Catalyzed Cyclo-oligomerization of Isocyanates

Zoltán Pusztai, Gábor Vlád, Andrea Bodor, István T. Horváth, Hans J. Laas, Reinhard Halpaap, and Frank U. Richter, Angew. Chem. Int. Ed., 2006, 45, 107-110. PDF +Supporting Information, Angew. Chem., 2006, 118, 113-116. PDF

Book Chapters

• Polymerization – Homogeneous, in Encyclopedia of Catalysis, ed. István. T. Horváth, John Wiley & Sons, New Jersey, 2003, Vol. 5, p611-737. LINK TO THE BOOK / CHAPTER

Awards

• 10th place, National Secondary School Competition, 1997., Teacher: Nadrainé Horváth Katalin, Eötvös József Secondary School, Budapest, Hungary.
• Award of the Head of Chemistry Department, Scientific Student Conference, ELTE, Budapest, Hungary, 2000.

Language Skills

• English
• Esperanto

Computer Skills

• MS Windows 95, 98(SE), ME, 2000 WS, XP Prof.
• MS Word, Excel, PowerPoint, FrontPage
• ChemDraw, Chem3D, IsisDraw, ReactIR v2.x, Bruker XWIN-NMR és WIN-NMR
• Corel Draw, Adobe Photoshop, Adobe Acrobat, Microcal Origin

Hobby

• Sport: Bicycle, Running, Ice Skating, Basketball, Football, Swimming, Kayak, Bowling, Pool.
• Computer: hardware.
• Others: Digital Photo, Reading (Agatha Christie, Jules Verne, Colin Forbes, Stephen W. Hawking), Excursions, Travelling, Music (Secret Garden, Blackmore’s Night, Astor Piazzolla, Oscar Peterson, Liszt Ferenc, Tomasso Albinoni, Frédéric Chopin, Johannes Brahms, Ludwig van Beethoven, Edvin Marton, Dido, Enigma), Hi-Fi, Chess, Tikal, Catan.